BACKGROUND:The association between human leukocyte antigen (HLA) genes (located in the Major Histocompatibility Complex [MHC] region of chromosome 6p21) and NPC has been known for some time.Recently, two genome-wide association studies (GWAS) conducted in Taiwan and China confirmed that the strongest evidence for NPC association was mapped to the M

Apicomplexan parasites are a group of protists that cause disease in humans and include pathogens like Plasmodium spp., the causative agent of malaria, and Toxoplasma gondii , the etiological agent of toxoplasmosis and one of the most ubiquitous human parasites in the world.Membrane contact sites (MCSs) are widespread structures within eukaryotic c

Metastasis is the primary cause of cancer patient morbidity and mortality, but due to persisting gaps in our knowledge, it remains untreatable.Metastases often occur as patient tumors progress or recur after initial therapy.Tumor recurrence at the primary site may be driven by a cancer stem-like cell or tumor progenitor cell, while recurrence at a

Non-invasive transcranial stimulation of cerebellum and primary motor cortex (M1) has been shown to enhance motor learning.However, the mechanisms by which stimulation improves learning remain largely unknown.Here, we sought to shed light on the neural correlates of transcranial direct current stimulation (tDCS) during motor learning by simultaneou

Investigation of the bi-directional relationship between natural killer (NK) cells and plasmacytoid dendritic cells (pDCs) is critical in understanding antiviral immunity.In the present study, we determined whether the tumor necrosis factor apoptosis-inducing ligand (TRAIL) pathway was responsible for increased apoptosis of pDCs Canvas Picture in h